Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: * A standard steroid injection * Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection * PNS therapy in combination with a placebo injection Steroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients diagnosed with chronic knee pain (baseline pain score \>=4), seen at Pain Management Center at MD Anderson Cancer Center; if patient has bilateral knee pain, the side with the more severe knee pain will be treated first and counted towards the primary and secondary endpoints

• Patients between ages 18-85 years old

• Patient signed informed consent

Locations
United States
Texas
M D Anderson Cancer Center
RECRUITING
Houston
Contact Information
Primary
Saba Javed, MD
sjaved@mdanderson.org
(713) 792-9530
Time Frame
Start Date: 2023-08-10
Estimated Completion Date: 2026-01-31
Participants
Target number of participants: 45
Treatments
Experimental: Group 1 (standard steroid injection)
Participants will receive 1 standard steroid injection.
Experimental: Group 2 (PNS therapy plus 1 standard steroid injection).
Participants will receive PNS therapy plus 1 standard steroid injection.
Experimental: Group 3 (PNS therapy plus 1 placebo injection)
Participants will receive PNS therapy plus 1 placebo injection.
Related Therapeutic Areas
Sponsors
Leads: M.D. Anderson Cancer Center

This content was sourced from clinicaltrials.gov